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    刘旭杰 副教授

    作者: 时间:2019-01-10 点击数:

     

     

    刘旭杰  LIU Xujie  副教授

    所属学院:生物医药学院

    导师类型:硕士生导师

    E-mailliuxujie@gdut.edu.cn

     

    科研方向:

    1PK10彩票、多功能生物材料的开发与应用PK10彩票,包括药物缓释材料、骨修复材料PK10彩票、siRNA载体材料等

    2、材料与细胞相互作用,材料诱导组织再生

     

    个人简介:

    刘旭杰,博士,副教授。20203月以“青年百人计划”A层次引进到广东工业大学制药工程系工作。在药物缓释材料、骨修复生物材料PK10彩票,组织工程PK10彩票、基因递送系统等多学科交叉领域具有多年的研究经验。先后主持自然科学基金青年基金,博士后特别资助和一等资助,以及深圳市基础研究项目等项目,参与国家重点研发计划、科技部国际合作交流项目、自然科学基金等国家级省部级项目。发表SCI论文40余篇(其中以第一作者和通讯作者身份在领域TOP期刊ACS Applied Materials & Interfaces, Acta Biomaterialia, Theranostics等杂志发表论文16篇),谷歌学术搜索被引次数700+次,H因子17。2016入选Tissue Engineering杂志Young Investigator Council,担任ACS Applied Materials & Interfaces, Tissue Engineering, Biomaterials Science, Colloids and Surfaces B, Biomedical Materials, Applied Surface Science等国际期刊审稿人PK10彩票,博士论文被中国知网选为优秀学位论文样例出版PK10彩票。

     

    教育背景:

    2010/09-2015/07PK10彩票,清华大学,材料学院,博士

    2013/04-2013/09,德国美因茨大学,交换生

    2006/09-2010/06,华中科技大学,材料科学与工程学院PK10彩票,学士

     

    工作经历:

    2020/03至今,广东工业大学“青年百人计划A类”,生物医药学院PK10彩票,副教授

    2018/01-2020/01PK10彩票,美国凯斯西储大学,博士后

    2015/11-2017/11,清华大学,深圳研究生院,博士后

     

    科研项目:

    1. 国家自然科学基金青年科学基金项目PK10彩票PK10彩票,31600763,表面形貌梯度和表面化学共同调控细胞行为及相关机理,2017/01-2017/12,10.8万元,主持

    2. 中国博士后科学基金特别资助PK10彩票,等离子体聚合构建表面调控细胞成骨分化,2017T100073,15万,主持

    3. 中国博士后科学基金面上资助(一等),等离子体聚合构建表面化学及形貌梯度共同影响细胞行为,2017M610084,8万PK10彩票,主持

    4. 深圳市科创委基础研究(自由探索)项目,JCYJ20160531195524566,新型巯基化壳聚糖/碳酸钙复式微球用于骨组织工程研究PK10彩票,2016/08-2018/08,30万元PK10彩票,主持

    5. 国家重点研发计划生物医用材料研发与组织器官修复替代重点专项,2016YFC1100100,基于天然细胞外基质的系列智能凝胶原位诱导非骨组织再生的机制与理论研究,2016/07-2020/12, 1250万元,参加

    6. 国家自然科学基金面上项目,81672158,新型生物活性墨水原位打印诱导骨再生研究,2017/01-2020/12,60万元,参加

    7. 国家自然科学基金面上项目PK10彩票,81671829PK10彩票,磁性鸡尾酒功能型水凝胶用于三阴乳腺癌综合治疗的研究,2017/01-2020/12,60万元,参加

    8. 科技部国际科技合作项目PK10彩票,2015DFG52490,纳米粒子对间充质干细胞分化的影响,2015/04-2017/04PK10彩票,60万元,在研,参加

    9. 国家自然科学基金面上项目,51472139,几种无机纳米粒子对干细胞分化的影响及相关机理PK10彩票,2015/01-2018/12,83万元,参加

     

    主要论文:

    迄今为止PK10彩票,共发表SCI论文40余篇,仅列第一作者和通讯作者身份论文,详细论文可见https://www.researchgate.net/profile/Xujie_Liu

    (1) Xujie Liu, Amita M. Vaidya, Da Sun, Yan Zhang, Nadia Ayat, Andrew Schilb and Zheng Rong Lu, Role of eIF4E on epithelial‐mesenchymal transition, invasion, and chemoresistance of prostate cancer cells. Cancer Communications, 2020, 40(2-3):126-131. (SCI,IF: 3.62)

    (2) Xujie Liu, Yong Xie, Shengjun Shi, Qingling Feng, Akash Bachhuka, Xiaodong Guo, Zhending She, Rongwei Tan, Qiang Cai, and Krasimir Vasilev, The co-effect of surface topography gradient fabricated via immobilization of gold nanoparticles and surface chemistry via deposition of plasma polymerized film of allylamine/acrylic acid on osteoblast-like cell behavior. Applied Surface Science, 2019, 473: 838-847. (SCIPK10彩票,IF: 5.155)

    (3) Xie, Yong, Xujie Liu*, Xinxin Ma, Yuefeng Duan, Youwei Yao, and Qiang Cai*, Small Titanium-Based MOFs Prepared with the Introduction of Tetraethyl Orthosilicate and Their Potential for Use in Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10 (16): 13325-13332. (* Corresponding author) SCI,IF: 8.456

    (4) Xujie Liu, Yong Xie, Rui Liu, Ranran Zhang, Hao Yan, Xing Yang, Qianli Huang, Wei He, Bo Yu, Qingling Feng, Shengli Mi, Qiang Cai, A Cyclo-trimer of Acetonitrile Combining Fluorescent Property with Ability to Induce Osteogenesis and Its Potential as Multifunctional Biomaterial. Acta Biomaterialia, 2018, 65: 163-173. (SCI,IF: 6.638)

    (5) Xie, Yong, Xinxin Ma, Xujie Liu*, Qingming Long, Yu Wang, Youwei Yao, and Qiang Cai*, Carrier-free microspheres of an anti-cancer drug synthesized via a sodium catalyst for controlled-release drug delivery. Materials, 2018, 11 (2): 281. (* Corresponding author)(SCIPK10彩票,IF: 2.972

    (6) Fanlu Zhuo, Xujie Liu*, Qin Gao, Ying Wang, Kun Hu, Qiang Cai*, Injectable Hyaluronan-Methylcellulose Composite Hydrogel Crosslinked by Polyethylene Glycol for Central Nervous System Tissue Engineering. Materials Science and Engineering: C, 2017, 81(1):1-7. (* Corresponding author)(SCIPK10彩票,IF: 4.959

    (7) Feng Zeng, Qiang Cai*, Xujie Liu*, Youwei Yao*, Fanlu Zhuo, Qin Gao, Yong Xie, Yu Wang, Fabrication and mechanical properties of mesoporous silica nanoparticles reinforced magnesium matrix composite. Journal of Alloys and Compounds, 2017, 728:413-423. (* Corresponding author)(SCI,IF: 4.175

    (8) Yan Chen#, Xujie Liu#, Rui Liu#, Yong Gong, Mingbo Wang, Qianli Huang, Bo Yu, Qingling Feng, Zero-order controlled release of BMP2-derived peptide P24 from the chitosan scaffold by chemical grafting modification technique for promotion of osteogenesis in vitro and enhancement of bone repair in vivo, Theranostics, 2017, 7(5):1072. (# co-first author)SCI,IF: 8.063

    (9) Xujie Liu, Tarek Elkhooly, Ranran Zhang, Qingling Feng, Akash Bachhuka, Krasimir Vasilev, Qiang Cai, Shengli Mi, Selective Deposition of CaCO3 on Chemical Gradient Surface Generated by Plasma Polymerization and Its Effect on Cell Adhesion. Materials letters, 2017, 186: 90-93. SCI,IF: 3.019

    (10) Xujie Liu, Bo Yu, Qianli Huang, Rui Liu, Qingling Feng, Qiang Cai, Shengli Mi, In vitro BMP-2 Peptide Release from Thiolated Chitosan Based Hydrogel. International Journal of Biological Macromolecules, 2016, 93: 314-321. SCI,IF: 4.784

    (11) Xujie Liu, Tarek Elkhooly, Qianli Huang, Wei He, Qiang Cai, Qingling Feng, Shengli Mi, A facile way to prepare mesoporous spherical calcites controlled by chondroitin sulfate for shape and carboxymethyl chitosan for size. CrystEngComm, 2016, 8 (44): 8582-8586. SCI,IF: 3.382

    (12) Xujie Liu, Shengjun Shi, Qingling Feng, Akash Bachhuka, Wei He, Qianli Huang, Ranran Zhang, Xing Yang, Krasimir Vasilev, Surface Chemical Gradient Affects the Differentiation of Human Adipose-Derived Stem Cells via ERK1/2 Signaling Pathway. ACS Applied Materials & Interfaces, 2015, 7(33): 18473-18482. SCIPK10彩票,IF: 8.456

    (13) Xujie Liu, Qingling Feng, Akash Bachhuka, Krasimir Vasilev, Surface Modification by Allylamine Plasma Polymerization Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells. ACS Applied Materials & Interfaces, 2014, 6 (12): 9733-9741. SCI,IF: 8.456

    (14) Xujie Liu, Yan Chen, Qianli Huang, Wei He, Qingling Feng, Bo Yu, A Novel Thermo-Sensitive Hydrogel Based On Thiolated Chitosan/Hydroxyapatite/ Beta-Glycerophosphate. Carbohydrate Polymers, 2014, 110: 62-69. SCIPK10彩票,IF: 6.044

    (15) Xujie Liu, Wei He, Zhou Fang, Arne Kienzle, Qingling Feng, Influence of Silver Nanoparticles On Osteogenic Differentiation of Human Mesenchymal Stem Cells. Journal of Biomedical Nanotechnology, 2014, 10 (7): 1277-1285. SCI,IF: 5.068

    (16) Xujie Liu, Qingling Feng, Akash Bachhuka, Krasimir Vasilev, Surface Chemical Functionalities Affect the Behavior of Human Adipose-Derived Stem Cells in Vitro. Applied Surface Science, 2013, 270, 473-479. SCI,IF: 5.155

    (17) 刘旭杰, 高永华, 冯庆玲, 不同化学官能团对无机相碳酸钙晶体的调控. 复合材料学报, 2012, 29 (1): 21-27. EI

     

    发明专利

    (1) 刘旭杰; 李小宁; 解勇; 一种巯基化壳聚糖/碳酸钙复式微球及其制备方法, 2017

    -9-26, 中国, CN201710881333.3.

    (2) 冯庆玲; 刘旭杰; 于博; 陈彦; 刘睿; 一种接多肽壳聚糖/羟基磷灰石/珍珠粉支

    架的制备方法, 2014-9-10, 中国, CN201410273052.6.

    (3) 蔡强; 解勇; 刘旭杰; 姚有为; 一种以苯乙腈合成2,6-二苄基-5-苯基-4-氨基嘧

    啶的方法, 2016-12-27 中国, CN201611226467.3

     

     

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